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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GBA3
All Species:
27.58
Human Site:
Y359
Identified Species:
67.41
UniProt:
Q9H227
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H227
NP_001121904.1
469
53696
Y359
G
V
C
K
L
L
K
Y
I
K
D
T
Y
N
N
Chimpanzee
Pan troglodytes
XP_517125
469
53674
Y359
G
V
R
K
L
L
K
Y
I
K
D
T
Y
N
N
Rhesus Macaque
Macaca mulatta
XP_001105060
469
53778
Y359
G
V
R
K
L
L
K
Y
I
K
D
T
Y
N
N
Dog
Lupus familis
XP_545975
469
53689
Y359
G
I
R
K
L
L
K
Y
I
K
D
T
Y
N
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1F9
566
64807
F396
G
F
R
R
L
L
N
F
A
Q
T
Q
Y
G
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513443
542
60826
Y432
G
L
R
K
L
L
K
Y
I
K
D
T
Y
N
N
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087678
499
56923
Y364
G
L
R
K
L
L
K
Y
I
K
K
T
F
N
N
Zebra Danio
Brachydanio rerio
NP_001018529
475
53419
Y362
G
L
R
K
L
L
K
Y
I
K
D
T
Y
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792769
548
61806
K398
W
G
I
R
R
L
V
K
W
V
H
D
E
Y
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FIW4
490
56058
Y374
G
I
R
K
T
L
N
Y
M
S
K
K
Y
N
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.6
87.8
N.A.
36.7
N.A.
N.A.
67.3
N.A.
58.3
52.2
N.A.
N.A.
N.A.
N.A.
43.2
Protein Similarity:
100
99.5
98.9
94
N.A.
53
N.A.
N.A.
76.9
N.A.
73.5
69
N.A.
N.A.
N.A.
N.A.
58.9
P-Site Identity:
100
93.3
93.3
86.6
N.A.
26.6
N.A.
N.A.
86.6
N.A.
73.3
73.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
53.3
N.A.
N.A.
93.3
N.A.
86.6
86.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
60
10
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% E
% Phe:
0
10
0
0
0
0
0
10
0
0
0
0
10
0
0
% F
% Gly:
90
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% H
% Ile:
0
20
10
0
0
0
0
0
70
0
0
0
0
0
0
% I
% Lys:
0
0
0
80
0
0
70
10
0
70
20
10
0
0
0
% K
% Leu:
0
30
0
0
80
100
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
20
0
0
0
0
0
0
70
60
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% Q
% Arg:
0
0
80
20
10
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% S
% Thr:
0
0
0
0
10
0
0
0
0
0
10
70
0
10
0
% T
% Val:
0
30
0
0
0
0
10
0
0
10
0
0
0
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
80
0
0
0
0
80
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _